Dr. Reju-All Advanced Retino-Mela Serum

Advanced brightening and anti-aging serum formulated with Hydroxypinacolone Retinoate (HPR), niacinamide, tranexamic acid, panthenol, and soothing ingredients to help improve hyperpigmentation, uneven skin tone, fine lines, and skin texture. Dr. Reju-All Advanced Retino-Mela Serum delivers the benefits of a next-generation retinoid while remaining gentler than traditional retinol formulas.

This lightweight serum targets dark spots, post-acne marks, and early signs of aging while supporting the skin barrier for a smoother, brighter, and more even complexion.

Main benefits

• helps reduce dark spots and hyperpigmentation
  
• improves uneven skin tone and post-acne marks
  
• smooths the appearance of fine lines and wrinkles
  
• refines skin texture and visible pores
  
• supports collagen production and skin renewal
  
• helps maintain a healthy skin barrier with minimal irritation compared to traditional retinol formulas 

Key ingredients

• Hydroxypinacolone Retinoate (HPR) is a next-generation retinoid that helps improve wrinkles, skin texture, and elasticity with less irritation than traditional retinol 
  
• niacinamide (10%) helps brighten the complexion and strengthen the skin barrier 
  
• tranexamic acid (4%) helps improve hyperpigmentation and stubborn dark spots 
  
• panthenol helps soothe and support barrier repair 
  
• bisabolol helps calm irritation and redness 
  
• sodium hyaluronate helps maintain hydration and skin suppleness 

Best for skin types

• hyperpigmentation-prone skin
  
• post-acne marks
  
• normal skin
  
• combination skin
  
• oily skin
  
• retinoid beginners looking for a gentler option
  
• mature skin concerned with fine lines and uneven tone

How to use

• apply in the evening after cleansing and toner
  
• use 2–3 times per week when starting
  
• gradually increase frequency as tolerated
  
• follow with a moisturizer
  
• wear sunscreen daily during the daytime
  
• avoid combining with strong exfoliating acids on the same night when first introducing the product 

Bubu Tip

If your main concern is post-inflammatory hyperpigmentation or acne marks, this serum is more targeted than a standard retinol serum thanks to the combination of HPR, 10% niacinamide, and 4% tranexamic acid. It's a great option for customers who want both anti-aging and brightening benefits in one product.

Clean formula focus

• fragrance-free formula
  
• combines brightening and anti-aging care
  
• suitable for sensitive retinoid users
  
• lightweight serum texture
  
• barrier-supporting ingredients included alongside active ingredients